What polynucleotides actually does, what it costs in Spain, and what a clinic has to hold on the public register before it can legally offer it to you.
What it is
Polynucleotides, known clinically as polynucleotide injections. A clinic offering it needs the matching unit on its entry in the national register of health centres, and the doctor performing it needs the qualification that unit implies. Both are public and both take five minutes to check.
What it costs
What the quote should include
A surgical quote in Spain normally covers the pre-operative tests, the theatre, the anaesthetist and the follow-ups. A non-surgical quote covers the product and the session. Normally is not always, and an itemised written quote is your right here.
What pushes it up
City, the seniority and specialty of the doctor, the product or device, the number of areas, and whether a general anaesthetic is involved. VAT at 21 per cent applies to purely aesthetic treatment; treatment with a therapeutic purpose is exempt. Ask which you are being quoted.
When a price is too low
A figure far below the bottom of that range usually means a diluted or non-original product, a practitioner without the qualification the treatment requires, or a quote that omits something you will be charged for later. Ask which, in writing.
Before you book
Ask who performs it and what their official qualification is, ask to see the registry authorisation, ask for the itemised quote including VAT, and ask what happens if you are not happy. A clinic that answers all four without hesitating is telling you something useful.
Want us to find you a clinic for polynucleotides?
Tell us what you want done and where. We run the registry check and the medical-register check ourselves and send you what we found, including the parts we could not confirm. Free, and no clinic gets your details unless you ask.
Ask us to find one →Next to this
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Clinics we have checked
Ranked by how little is left unanswered, not by who pays us. Three so far, and we publish the working for each one.
- Top pick
SMD Clinic
Villanueva de la Cañada, Madrid
A family-run dental and aesthetic medicine practice west of Madrid, not a franchise.
- 4 checks passed
- 3 still open
- Address and phone published
- 02
Clínica Bayón
Madrid
A central Madrid aesthetic medicine practice built around facial rejuvenation and ageing management.
- 4 checks passed
- 4 still open
- Address and phone published
- 03
DT Clinic Madrid
Madrid
A Madrid cosmetic surgery practice working across body and facial procedures.
- 2 checks passed
- 4 still open
- No public phone number yet
Listed, not yet checked
68 more we can tell you something true about
Every practice below has its own live website and one public marker we looked at ourselves, linked on each card. That is not our full check, and we say so on every one. Take the eight questions with you.
Derma Clinic Spain
SEME doctorAlfaz del Pi, Alicante•dermatology, hair transplant, injectables
Dermatology, hair restoration and aesthetic medicine clinic in Albir, working in English and French.
What we can see: SEME lists its doctor at this address with colegiado 030309033, health authorisation U.48 22769 and the SEME quality seal since February 2025. source
Still to check: REGCESS registry number on the clinic's own site, colegiado numbers for the other two doctors
Their website →Clinica Kyra
SECPRE surgeonAlicante, Alicante•plastic surgery, injectables, dermatology
Plastic surgery and aesthetic medicine clinic in Alicante with two SECPRE-listed surgeons.
What we can see: Two surgeons in the SECPRE Alicante directory, one with this clinic as his listed address. The site publishes both colegiado numbers. source
Still to check: REGCESS registry number
Their website →Clinicas Comyce
SEME doctorAlicante, Alicante•injectables, laser hair removal, weight loss
Aesthetic medicine clinic in Alicante, with further branches in Benidorm and Alcoy.
What we can see: SEME lists its doctor with colegiado 030306111, health authorisation U.48 1961 and the SEME quality seal since October 2022. source
Still to check: REGCESS registry number on the clinic's own site
Their website →Instituto Perez de la Romana
SECPRE surgeonAlicante, Alicante•plastic surgery, body contouring, injectables
Plastic surgery practice in Alicante led by Dr Federico Perez de la Romana.
What we can see: Listed in the SECPRE member directory for Alicante province, which names this practice as his consulting address. source
Still to check: REGCESS registry number, colegiado number
Their website →CIMEA
SEME doctorArrecife, Las Palmas•injectables, skin treatments
Aesthetic and anti-ageing medicine practice in Arrecife, Lanzarote.
What we can see: SEME lists the doctor at the Rambla Medular address published on his own site. source
Still to check: REGCESS registry number, colegiado number
Their website →Maive
SEME doctorArrecife, Las Palmas•injectables, skin treatments, plastic surgery
Aesthetic medicine and surgery centre in Arrecife, Lanzarote, with three named doctors.
What we can see: The homepage publishes health authorisation SCS/7776. SEME lists a doctor at the same address. source
Still to check: national REGCESS code, colegiado numbers for the three named doctors
Their website →Antiaging Group Barcelona
SECPRE surgeonBarcelona, Barcelona•plastic surgery, injectables, body contouring
Plastic surgery and aesthetic medicine clinic on Ronda del General Mitre, Barcelona.
What we can see: The homepage shows membership of SECPRE, SCCPRE, AECEP, SEME and ISAPS, and names its plastic surgeons individually. source
Still to check: REGCESS registry number, colegiado numbers
Their website →Clinica Dra. Laura Situ
SEME doctorBarcelona, Barcelona•injectables, skin treatments
Aesthetic medicine practice on Paseo de la Bonanova, Barcelona.
What we can see: The site publishes the Generalitat health registry number E08698748, the colegiada number 41424 and SEME membership. source
Still to check: founding year
Their website →Clinica Planas
SECPRE surgeonBarcelona, Barcelona•plastic surgery, injectables
Plastic surgery and aesthetic medicine clinic in Sarria-Sant Gervasi, Barcelona.
What we can see: The clinic's own profile for its medical director states membership of SECPRE, SCCPRE, ISAPS and AECEP. source
Still to check: REGCESS registry number, colegiado numbers of the surgeons
Their website →Clinica Provenca
SEME doctorBarcelona, Barcelona•injectables, skin treatments
Facial, body and hair aesthetic medicine practice on Roger de Lluria, Barcelona.
What we can see: The site publishes the COMB colegiado number 55671, SEME membership number 2729 and the COMB DIACAP diploma. source
Still to check: REGCESS registry number, founding year
Their website →Instituto Clinico Estetico
Doctors namedBarcelona, Barcelona•injectables, hair transplant, laser hair removal
Aesthetic medicine, hair and laser centre on Roger de Lluria, Barcelona.
What we can see: The legal notice publishes authorisation E08744225 in the Catalan register of health centres. source
Still to check: names and colegiado numbers of the doctors, founding year
Their website →Instituto Dr. Serra Mestre
SECPRE surgeonBarcelona, Barcelona•plastic surgery, injectables
Plastic surgery and aesthetic medicine practice at the Hospital Quironsalud Barcelona.
What we can see: The site states membership of SECPRE, SEMAL, SETGRA and SICPRE, and publishes the consulting address. source
Still to check: REGCESS registry number, colegiado number
Their website →Instituto de Dermatologia Doctor Ignacio Umbert
Doctors namedBarcelona, Barcelona•dermatology, injectables, skin treatments
Dermatology and aesthetic medicine practice on Plaza Manuel Corachan, Barcelona.
What we can see: The site names its founding director, publishes two Barcelona consulting addresses and states a Mohs surgery unit. source
Still to check: REGCESS registry number, colegiado number
Their website →Serena Clinic
SEME doctorBarcelona, Barcelona•injectables, skin treatments, laser hair removal
Aesthetic medicine, laser and nutrition clinic on Maria Cubi, Barcelona.
What we can see: The legal notice publishes health registry E08571364. The site publishes two colegiado numbers and states SEME and SELMQ membership. source
Still to check: founding year
Their website →Clinica Verdesoto Premium
SEME doctorBenidorm, Alicante•injectables, weight loss, skin treatments
Aesthetic medicine and weight management clinic in Benidorm run by Dra Nuria Verdesoto.
What we can see: SEME member 1062 since 2004, colegiado 030308997, health authorisation U.48 11348 and the SEME quality seal since May 2026. source
Still to check: REGCESS registry number on the clinic's own site, founding year
Their website →Dr. Stephane Serrano Medicina Estetica
SEME doctorBenidorm, Alicante•injectables, skin treatments
Aesthetic medicine practice with clinics in Benidorm and Calpe.
What we can see: The site publishes colegiado 030307906 and SEME membership 2620; both match the SEME directory entry, which adds U.48 21025. source
Still to check: REGCESS registry number
Their website →CDC Clinica Diaz Caparros
SEME doctorCartagena, Murcia•injectables, skin treatments
Aesthetic medicine and laser clinic on Calle Carmen, Cartagena, run by an ENT specialist.
What we can see: SEME member 1490 since 2012 with colegiado 303004992, health authorisation U.48 40002616 and the SEME quality seal since October 2022. source
Still to check: REGCESS registry number, the split between ENT and aesthetic activity
Their website →Dra. Belen Gornes Cirugia Plastica
SECPRE surgeonCiutadella de Menorca, Baleares•plastic surgery, injectables
Plastic surgery practice with consulting rooms in Ciutadella and Mahon, Menorca.
What we can see: Listed in the SECPRE member directory for Baleares, which names the Ciutadella practice and address. source
Still to check: REGCESS registry number, colegiado number
Their website →Clinica ICA
SEME doctorCosta Adeje, Santa Cruz de Tenerife•plastic surgery, body contouring, injectables
Surgery and aesthetic medicine group with sites in Costa Adeje, La Orotava and Puerto de la Cruz.
What we can see: SEME lists a doctor at the Costa Adeje address the clinic publishes on its own site. source
Still to check: REGCESS registry number, colegiado numbers for any of the seven named doctors
Their website →DeLarra Clinic
SEME doctorDenia, Alicante•injectables, hair transplant, body contouring
Aesthetic medicine, vascular and hair transplant clinic at Jesus Pobre, Denia.
What we can see: The site publishes its own Comunidad Valenciana registry number 22204, matching the U.48 code in the doctor's SEME entry. source
Still to check: colegiado number on the clinic's own site, national REGCESS entry
Their website →BERMA
SEME doctorElche, Alicante•injectables, body contouring, skin treatments
Aesthetic medicine and nutrition clinic at Arenales del Sol, Elche.
What we can see: SEME member 2718 with colegiado 462869247, health authorisation U.48 24839 and the SEME quality seal since February 2026. source
Still to check: REGCESS registry number on the clinic's own site, a street address on the clinic's own site
Their website →Artistry Clinic
SEME doctorEstepona, Malaga•plastic surgery, injectables, skin treatments
Aesthetic medicine and surgery clinic in Estepona founded by Dr Agassi Charchoglyan.
What we can see: Health centre number NICA 56412 published in the footer of every page. A doctor at that address is listed in the SEME Malaga directory. source
Still to check: REGCESS registry number, colegiado number for the founder
Their website →Clinica Estetica Incorpore
SEME doctorFuengirola, Malaga•injectables, skin treatments, body contouring
Aesthetic medicine clinic with sites in Fuengirola and Malaga.
What we can see: Dr Juan Enrique Perez Enriquez listed in the SEME member directory for Malaga at both addresses the clinic publishes. source
Still to check: REGCESS registry number, NICA number
Their website →Clinica Dra. Laura Fernandez
SEME doctorIbiza, Baleares•injectables, skin treatments, dermatology
Aesthetic medicine clinic in Ibiza with dermatology, nutrition and a hair surgery unit.
What we can see: SEME publishes colegiado 070707371 for its doctor, the Paseo Juan Carlos I address, and health authorisation U.48 4382. source
Still to check: REGCESS registry number, who performs the hair surgery it advertises
Their website →
44 more listed in the full directory.
